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USDA Patents Microbes To Fight Wheat Fungus


Four yeasts and three bacteria that live on flowering wheat heads, but cause no harm there, have been patented by the U.S. Department of Agriculture (USDA) as biological control agents in the fight against Fusarium head blight (FHB).

Caused by the fungus Fusarium graminearum, FHB is among the most costly diseases of cereal crops worldwide, including wheat, barley and oats. From 1998 to 2000, FHB epidemics in U.S. small grains inflicted an estimated $2.7 billion worth of losses, notes David Schisler. He is a plant pathologist with the Agricultural Research Service (ARS), USDA's chief scientific research agency.

The fungus infects wheat through its flower tissues, including anthers. But competition for space and nutrients there is fierce, according to studies by Schisler and colleagues at the ARS National Center for Agricultural Utilization Research in Peoria, Ill., and at Ohio State University (OSU) in Columbus. Indeed, some of the bacteria and yeasts that the researchers isolated from wheat

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Phase II (IDdb). Small-scale testing in the target population, to assess therapeutic effects and to establish dose levels for phase III trials.

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